Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury?

Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury?

Background/Aims: Hyponatremia associated with high urinary fractional excretion of uric acid which persists after serum sodium is corrected is the cardinal feature of salt losing nephropathy (SLN). We hypothesize that low grade proximal tubular injury is present in SLN because the proximal tubule is...

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Bibliographic Details
Main Authors: S.-M.Kurt Lee, Miguel A. Lanaspa, Laura G. Sánchez-Lozada, Richard J. Johnson
Format: Article
Language:English
Published: Karger Publishers 2016-08-01
Series:Kidney & Blood Pressure Research
Subjects:
Hyponatremia
Uric acid
Proximal tubule
Fructose
Salt losing nephropathy
Online Access:http://www.karger.com/Article/FullText/447928

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