Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands

Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands

Abstract Background The Open Targets Platform integrates different data sources in order to facilitate identification of potential therapeutic drug targets to treat human diseases. It currently provides evidence for nearly 2.6 million potential target-disease pairs. G-protein coupled receptors are a...

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Bibliographic Details
Main Authors: Johannes M Freudenberg, Ian Dunham, Philippe Sanseau, Deepak K Rajpal
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Bioinformatics
Subjects:
G-protein coupled receptors
Drug discovery
Data integration
Target identification
Online Access:http://link.springer.com/article/10.1186/s12859-018-2392-y

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