Structural Basis for the Interaction between p53 Transactivation Domain and the Mediator Subunit MED25

Structural Basis for the Interaction between p53 Transactivation Domain and the Mediator Subunit MED25

Eukaryotic transcription initiation is mediated by interactions between transcriptional activators and the mediator coactivator complex. Molecular interaction of p53 transcription factor with mediator complex subunit 25 (MED25) is essential for its target gene transcription. In this study, we charac...

Full description

Bibliographic Details
Main Authors: Min-Sung Lee, Kyungeun Lim, Mi-Kyung Lee, Seung-Wook Chi
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
p53
MED25
transactivation domain
protein-protein interaction
complex structure
nuclear magnetic resonance
Online Access:http://www.mdpi.com/1420-3049/23/10/2726

Internet

http://www.mdpi.com/1420-3049/23/10/2726

Similar Items