Scale Dependence of Structure-Function Relationship in the Emphysematous Mouse Lung

Scale Dependence of Structure-Function Relationship in the Emphysematous Mouse Lung

The purpose of this study was to determine how the initial distribution of elastase in mouse lungs determines the time course of tissue destruction and how structural heterogeneity at different spatial scales influences lung function. We evaluated lung function and alveolar structure in normal and e...

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Bibliographic Details
Main Authors: Susumu eSato, Erzsébet eBartolák-Suki, Harikrishnan eParameswaran, Hiroshi eHamakawa, Bela eSuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Physiology
Subjects:
Compliance
Inflammation
Lung
heterogeneity
airspace diameter
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00146/full

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