Up and down waves of glycemic control and lower-extremity amputation in diabetes

Abstract Lower extremity amputations (LEA) are associated with a high mortality and medical expenditure. Diabetes accounts for 45% to 70% of LEA and is one of the most potent risk factors for peripheral artery diseases (PAD). The existence of a link between the recent relaxation of glycemic targets...

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Bibliographic Details
Main Authors: Paola Caruso, Lorenzo Scappaticcio, Maria Ida Maiorino, Katherine Esposito, Dario Giugliano
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cardiovascular Diabetology
Online Access:https://doi.org/10.1186/s12933-021-01325-3