An algorithm to automatically determine the cycle length coverage to identify rotational activity during atrial fibrillation – a simulation study

• Main Authors: Kaltenbacher Wenzel, Rottmann Markus, Dössel Olaf
• Format: Article
• Language: English
• Published: De Gruyter 2016-09-01
• Series: Current Directions in Biomedical Engineering
• Subjects: atrial fibrillation; catheter ablation; cycle length coverage; dominant frequency; rotor
• Online Access: http://www.degruyter.com/view/j/cdbme.2016.2.issue-1/cdbme-2016-0038/cdbme-2016-0038.xml?format=INT
• ISSN: 2364-5504

Atrial fibrillation is the most common cardiac arrhythmia. Many physicians believe in the hypothesis that persistent atrial fibrillation is maintained by centers of rotatory activity. These so called rotors are sometimes found by physicians during catheter ablation or electrophysiological studies but there are also physicians who claim that they did not find any rotors at all. One reason might be that today rotors are mainly identified by visual inspection of the data. Thus we are aiming at an algorithm for rotor detection. We first developed an algorithm based on the local activation times of the intracardiac electrograms recorded by a multielectrode catheter that can automatically determine the cycle length coverage. This was done to get an objective view on possible rotors and therefore help to quantify whether a rotor was found or not. The algorithm was developed and evaluated in two different simulation setups, where it could reliably determine cycle length coverage. But we found out that effects like wave collision and slow conduction have strong influence on cycle length coverage. This prevents cycle length coverage from being suited as the only parameter to quantify whether a rotor is present or not. On the other hand we could confirm that rotors imply a cycle length coverage of >70% if the multielectrode catheter is centered in an area of <5 mm away from the rotor tip. Therefore cycle length coverage can at least be used in some situations to exclude the presence of possible rotors.