Novel in situ gelling vaginal sponges of sildenafil citrate-based cubosomes for uterine targeting

Novel in situ gelling vaginal sponges of sildenafil citrate-based cubosomes for uterine targeting

Sildenafil citrate (SIL), a type 5-specific phosphodiesterase inhibitor, demonstrates valuable results in the management of infertility in women; however, the absence of vaginal dosage form in addition to the associated oral adverse effects minimize its clinical performance. The present study is con...

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Bibliographic Details
Main Authors: Heba M. Aboud, Amira H. Hassan, Adel A. Ali, Abdel-Razik H. Abdel-Razik
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
sildenafil citrate
cubosomes
in-situ gelling sponges
uterine targeting
pharmacokinetic study
Online Access:http://dx.doi.org/10.1080/10717544.2018.1477858

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