A Combined Phytochemistry and Network Pharmacology Approach to Reveal the Potential Antitumor Effective Substances and Mechanism of Phellinus igniarius

A Combined Phytochemistry and Network Pharmacology Approach to Reveal the Potential Antitumor Effective Substances and Mechanism of Phellinus igniarius

Phellinus igniarius (P. igniarius) is a medicinal fungus that is widely used in East Asia for the adjuvant treatment of cancer. To elucidate the antitumor effective substances and mechanism of P. igniarius, we designed an approach incorporating cytotoxicity screening, phytochemical analysis, network...

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Bibliographic Details
Main Authors: Yu Dong, Ping Qiu, Rui Zhu, Lisha Zhao, Pinghu Zhang, Yiqi Wang, Changyu Li, Kequn Chai, Dan Shou, Huajun Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
Phellinus igniarius
antitumor
phytochemistry
network pharmacology
effective substances
mitochondrial apoptosis pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00266/full

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