Electrochemical Direct Determination of Catecholamines for the Early Detection of Neurodegenerative Diseases

• Main Author: Antonella Curulli
• Format: Article
• Language: English
• Published: MDPI AG 2009-04-01
• Series: Sensors
• Subjects: TiO2 nanostructured films; chemical sensors; monoamine-neurotransmitters; electrochemical transducers
• Online Access: http://www.mdpi.com/1424-8220/9/4/2437/

Smart (Nano) materials with biosensing functions posses enormous potential in development of new generation of stable biosensors, chemical sensors, and actuators. Recently, there is a considerable interest in using TiO2 nanostructured materials as a film-forming material since they have high surface area, optical transparency, high bio-compatibility, and relatively good conductivity. In this work, TiO2 nanostructured films were used as nanoporous electrodes to study the electron transfer mechanisms of dopamine. epinephrine and norepinephrine, in order to develop a new generation of chemical sensors. The interesting results obtained are described herein and the analytical characterization of these neurotransmitter sensors is reported.