Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections

Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections

Objective: Bone infections are challenging to treat because of limited capability of systemic antibiotics to accumulate at the bone site. To enhance therapeutic action, systemic treatments are commonly combined with local antibiotic-loaded materials. Nevertheless, available drug carriers have undesi...

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Bibliographic Details
Main Authors:	Stijn G. Rotman, Keith Thompson, Dirk W. Grijpma, Robert G. Richards, Thomas F. Moriarty, David Eglin, Olivier Guillaume
Format:	Article
Language:	English
Published:	Elsevier 2020-03-01
Series:	Journal of Orthopaedic Translation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X19301895

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