Cardiac leiomodin2 binds to the sides of actin filaments and regulates the ATPase activity of myosin.

Cardiac leiomodin2 binds to the sides of actin filaments and regulates the ATPase activity of myosin.

Leiomodin proteins are vertebrate homologues of tropomodulin, having a role in the assembly and maintenance of muscle thin filaments. Leiomodin2 contains an N-terminal tropomodulin homolog fragment including tropomyosin-, and actin-binding sites, and a C-terminal Wiskott-Aldrich syndrome homology 2...

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Bibliographic Details
Main Authors: Dávid Szatmári, Beáta Bugyi, Zoltán Ujfalusi, László Grama, Réka Dudás, Miklós Nyitrai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5638494?pdf=render

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