Engineering approaches for studying immune-tumor cell interactions and immunotherapy

Engineering approaches for studying immune-tumor cell interactions and immunotherapy

Summary: This review describes recent research that has advanced our understanding of the role of immune cells in the tumor microenvironment (TME) using advanced 3D in vitro models and engineering approaches. The TME can hinder effective eradication of tumor cells by the immune system, but immunothe...

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Bibliographic Details
Main Authors: Sarah E. Shelton, Huu Tuan Nguyen, David A. Barbie, Roger D. Kamm
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Components of the Immune System
Cancer
Bioengineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311822

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