Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids

Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids

The data presented in this article are related to the research article entitled “Generation of anti-oligosaccharide antibodies that recognize mammalian glycoproteins by immunization with a novel artificial glycosphingolipid” (Okuda and Fukui, 2018) [1]. This article describes the immunogenicity of a...

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Main Author: Tetsuya Okuda
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918305171
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spelling doaj-71b5b85346c5442e92b6c76e413d5d782020-11-25T02:11:09ZengElsevierData in Brief2352-34092018-08-0119256260Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acidsTetsuya Okuda0Bio-Design Research Group, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, JapanThe data presented in this article are related to the research article entitled “Generation of anti-oligosaccharide antibodies that recognize mammalian glycoproteins by immunization with a novel artificial glycosphingolipid” (Okuda and Fukui, 2018) [1]. This article describes the immunogenicity of a mammalian glycosphingolipid (globoside) carrying very long-chain fatty acids. Analysis of serum antibody titer by ELISA showed that this globoside had a strong immunogenicity in mice and could immediately induce production of anti-globoside IgGs. Isolated an IgG3 (κ) monoclonal antibody (mAb PA4.2) from the immunized mouse showed high specificity and reactivity against globoside. These data provide a novel antigen design method useful for obtaining IgG antibodies against glycosphingolipids.http://www.sciencedirect.com/science/article/pii/S2352340918305171
collection DOAJ
language English
format Article
sources DOAJ
author Tetsuya Okuda
spellingShingle Tetsuya Okuda
Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
Data in Brief
author_facet Tetsuya Okuda
author_sort Tetsuya Okuda
title Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
title_short Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
title_full Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
title_fullStr Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
title_full_unstemmed Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
title_sort data on immunoglobulin g antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2018-08-01
description The data presented in this article are related to the research article entitled “Generation of anti-oligosaccharide antibodies that recognize mammalian glycoproteins by immunization with a novel artificial glycosphingolipid” (Okuda and Fukui, 2018) [1]. This article describes the immunogenicity of a mammalian glycosphingolipid (globoside) carrying very long-chain fatty acids. Analysis of serum antibody titer by ELISA showed that this globoside had a strong immunogenicity in mice and could immediately induce production of anti-globoside IgGs. Isolated an IgG3 (κ) monoclonal antibody (mAb PA4.2) from the immunized mouse showed high specificity and reactivity against globoside. These data provide a novel antigen design method useful for obtaining IgG antibodies against glycosphingolipids.
url http://www.sciencedirect.com/science/article/pii/S2352340918305171
work_keys_str_mv AT tetsuyaokuda dataonimmunoglobulingantibodiesinducedbyimmunizationofmicewithglobosidecarryingverylongchainfattyacids
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