Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids
The data presented in this article are related to the research article entitled “Generation of anti-oligosaccharide antibodies that recognize mammalian glycoproteins by immunization with a novel artificial glycosphingolipid” (Okuda and Fukui, 2018) [1]. This article describes the immunogenicity of a...
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| Format: | Article |
| Language: | English |
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Elsevier
2018-08-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340918305171 |
| Summary: | The data presented in this article are related to the research article entitled “Generation of anti-oligosaccharide antibodies that recognize mammalian glycoproteins by immunization with a novel artificial glycosphingolipid” (Okuda and Fukui, 2018) [1]. This article describes the immunogenicity of a mammalian glycosphingolipid (globoside) carrying very long-chain fatty acids. Analysis of serum antibody titer by ELISA showed that this globoside had a strong immunogenicity in mice and could immediately induce production of anti-globoside IgGs. Isolated an IgG3 (κ) monoclonal antibody (mAb PA4.2) from the immunized mouse showed high specificity and reactivity against globoside. These data provide a novel antigen design method useful for obtaining IgG antibodies against glycosphingolipids. |
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| ISSN: | 2352-3409 |