1H NMR-based serum metabolomics reveals erythromycin-induced liver toxicity in albino Wistar rats

1H NMR-based serum metabolomics reveals erythromycin-induced liver toxicity in albino Wistar rats

Introduction: Erythromycin (ERY) is known to induce hepatic toxicity which mimics other liver diseases. Thus, ERY is often used to produce experimental models of drug-induced liver-toxicity. The serum metabolic profiles can be used to evaluate the liver-toxicity and to further improve the understand...

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Bibliographic Details
Main Authors: Atul Rawat, Durgesh Dubey, Anupam Guleria, Umesh Kumar, Amit K Keshari, Swati Chaturvedi, Anand Prakash, Sudipta Saha, Dinesh Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Erythromycin
metabolomics
multivariate data analysis
nuclear magnetic resonance
rats
liver-toxicity
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2016;volume=8;issue=4;spage=327;epage=334;aulast=Rawat

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2016;volume=8;issue=4;spage=327;epage=334;aulast=Rawat

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