An accurate formula to calculate exclusion power of marker sets in parentage assignment

<p>Abstract</p> <p>In studies on parentage assignment with both parents unknown, the exclusion power of a marker set is generally computed under the hypothesis that the potential families tested are independent and unrelated samples. This tends to produce overly optimistic exclusio...

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Bibliographic Details
Main Author: Vandeputte Marc
Format: Article
Language:deu
Published: BMC 2012-12-01
Series:Genetics Selection Evolution
Online Access:http://www.gsejournal.org/content/44/1/36
Description
Summary:<p>Abstract</p> <p>In studies on parentage assignment with both parents unknown, the exclusion power of a marker set is generally computed under the hypothesis that the potential families tested are independent and unrelated samples. This tends to produce overly optimistic exclusion power estimates. In this work, we have developed a new formula that gives almost unbiased results at the population level.</p>
ISSN:0999-193X
1297-9686