HIV antigen incorporation within adenovirus hexon hypervariable 2 for a novel HIV vaccine approach.

Adenoviral (Ad) vectors have been used for a variety of vaccine applications including cancer and infectious diseases. Traditionally, Ad-based vaccines are designed to express antigens through transgene expression of a given antigen. However, in some cases these conventional Ad-based vaccines have h...

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Bibliographic Details
Main Authors: Qiana L Matthews, Aiman Fatima, Yizhe Tang, Brian A Perry, Yuko Tsuruta, Svetlana Komarova, Laura Timares, Chunxia Zhao, Natalia Makarova, Anton V Borovjagin, Phoebe L Stewart, Hongju Wu, Jerry L Blackwell, David T Curiel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2910733?pdf=render