Assessment of the cardiovascular adverse effects of drug-drug interactions through a combined analysis of spontaneous reports and predicted drug-target interactions.

Assessment of the cardiovascular adverse effects of drug-drug interactions through a combined analysis of spontaneous reports and predicted drug-target interactions.

Adverse drug effects (ADEs) are one of the leading causes of death in developed countries and are the main reason for drug recalls from the market, whereas the ADEs that are associated with action on the cardiovascular system are the most dangerous and widespread. The treatment of human diseases oft...

Full description

Bibliographic Details
Main Authors:	Sergey Ivanov, Alexey Lagunin, Dmitry Filimonov, Vladimir Poroikov
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-07-01
Series:	PLoS Computational Biology
Online Access:	https://doi.org/10.1371/journal.pcbi.1006851

Similar Items

Prediction of Severity of Drug-Drug Interactions Caused by Enzyme Inhibition and Activation
by: Alexander Dmitriev, et al.
Published: (2019-10-01)

In Silico Prediction of Drug–Drug Interactions Mediated by Cytochrome P450 Isoforms
by: Alexander V. Dmitriev, et al.
Published: (2021-04-01)

Prediction of Protein–ligand Interaction Based on Sequence Similarity and Ligand Structural Features
by: Dmitry Karasev, et al.
Published: (2020-10-01)

Leveraging genetic interactions for adverse drug-drug interaction prediction.
by: Sheng Qian, et al.
Published: (2019-05-01)

Network-Based Analysis of OMICs Data to Understand the HIV–Host Interaction
by: Sergey Ivanov, et al.
Published: (2020-06-01)

Application of Data Mining and Statistical Approaches to Adverse Drug-Drug Interaction Prediction in Chemo Drug and Target Drug
by: Yung-Hsin Lin, et al.
Published: (2012)

Predicting drug-target interactions using drug-drug interactions.
by: Shinhyuk Kim, et al.
Published: (2013-01-01)

Data-driven prediction of adverse drug reactions induced by drug-drug interactions
by: Ruifeng Liu, et al.
Published: (2017-06-01)

Tools for prediction of xenobiotics interaction with human cytochrome P450
by: Poroikov V, et al.
Published: (2009-06-01)

Identifying and Characterizing Serious Adverse Drug Reactions Associated With Drug-Drug Interactions in a Spontaneous Reporting Database
by: Lara Magro, et al.
Published: (2021-01-01)

A Computational Approach for the Prediction of Treatment History and the Effectiveness or Failure of Antiretroviral Therapy
by: Olga Tarasova, et al.
Published: (2020-01-01)

SignalDetDDI: An SAS macro for detecting adverse drug-drug interactions in spontaneous reporting systems.
by: Masahiko Gosho, et al.
Published: (2018-01-01)

Spontaneous Reports of Serious Adverse Drug Reactions Resulting From Drug–Drug Interactions: An Analysis From the French Pharmacovigilance Database
by: Louis Létinier, et al.
Published: (2021-03-01)

Probabilistic Analysis for Detecting of Adverse Drug Events with Drug-Drug Interactions
by: Yu-Ting Huang, et al.
Published: (2007)

Potential Adverse Drug Events with Tetrahydrocannabinol (THC) Due to Drug–Drug Interactions
by: Joshua D. Brown
Published: (2020-03-01)

Adverse drug reactions and drug–drug interactions with over-the-counter NSAIDs
by: Moore N, et al.
Published: (2015-07-01)

An adverse drug interaction of haloperidol with levodopa
by: Jisha M Lucca, et al.
Published: (2015-01-01)

Adverse drug reactions induced by cardiovascular drugs in outpatients
by: Gholami K, et al.
Published: (2008-03-01)

QNA-Based Prediction of Sites of Metabolism
by: Olga Tarasova, et al.
Published: (2017-12-01)

Similarity-based machine learning framework for predicting safety signals of adverse drug–drug interactions
by: Heba Ibrahim, et al.
Published: (2021-01-01)

Computational models for the prediction of adverse cardiovascular drug reactions
by: Salma Jamal, et al.
Published: (2019-05-01)

CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds.
by: Alexey A Lagunin, et al.
Published: (2018-01-01)

Machine Learning for Drug-Target Interaction Prediction
by: Ruolan Chen, et al.
Published: (2018-08-01)

Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use
by: Joshua D. Brown, et al.
Published: (2019-07-01)

Drug-drug interactions and adverse drug reactions in polypharmacy among older adults: an integrative review
by: Maria Cristina Soares Rodrigues, et al.

Precision Medicine and Adverse Drug Reactions Related to Cardiovascular Drugs
by: James D. Noyes, et al.
Published: (2021-08-01)

Adverse Event Circumstances and the Case of Drug Interactions
by: Theodoros G. Soldatos, et al.
Published: (2019-03-01)

Prediction of drug-target interactions and drug repositioning via network-based inference.
by: Feixiong Cheng, et al.
Published: (2012-01-01)

Drug-Target Interaction Prediction Based on Drug Fingerprint Information and Protein Sequence
by: Yang Li, et al.
Published: (2019-08-01)

Prediction of Effective Drug Combinations by Chemical Interaction, Protein Interaction and Target Enrichment of KEGG Pathways
by: Lei Chen, et al.
Published: (2013-01-01)

Pharmacogenomics and circadian rhythms as mediators of cardiovascular drug-drug interactions
by: Yong-Jian Geng, et al.
Published: (2021-01-01)

Hospitalization due to Adverse Drug Reactions and Drug Interactions before and after HAART
by: Michelle M Foisy, et al.
Published: (2000-01-01)

Risk of drug interaction: combination of antidepressants and other drugs
by: Lincoln Sakiara Miyasaka, et al.

Risk of drug interaction: combination of antidepressants and other drugs
by: Miyasaka Lincoln Sakiara, et al.
Published: (2003-01-01)

Machine learning workflow to enhance predictions of Adverse Drug Reactions (ADRs) through drug-gene interactions: application to drugs for cutaneous diseases
by: Kalpana Raja, et al.
Published: (2017-06-01)

Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions
by: Min-Koo Choi, et al.
Published: (2021-04-01)

Assessment of non-compliance, adverse drug reactions, and drug interactions in patients with cardiovascular diseases admitted to medical wards at Songkhla Hospital
by: J Kanjanakiritamrong, et al.
Published: (2005-08-01)

Computational Discovery of Putative Leads for Drug Repositioning through Drug-Target Interaction Prediction.
by: Edgar D Coelho, et al.
Published: (2016-11-01)

Prediction of drug-target interactions for drug repositioning only based on genomic expression similarity.
by: Kejian Wang, et al.
Published: (2013-01-01)

DrugECs: An Ensemble System with Feature Subspaces for Accurate Drug-Target Interaction Prediction
by: Jinjian Jiang, et al.
Published: (2017-01-01)