PacBio Long Reads Improve Metagenomic Assemblies, Gene Catalogs, and Genome Binning

PacBio long reads sequencing presents several potential advantages for DNA assembly, including being able to provide more complete gene profiling of metagenomic samples. However, lower single-pass accuracy can make gene discovery and assembly for low-abundance organisms difficult. To evaluate the ap...

Full description

Bibliographic Details
Main Authors: Haiying Xie, Caiyun Yang, Yamin Sun, Yasuo Igarashi, Tao Jin, Feng Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.516269/full