(Epi)genomic heterogeneity of pancreatic islet function and failure in type 2 diabetes
Background: Pancreatic Islets of Langerhans are heterogeneous tissues consisting of multiple endocrine cell types that carry out distinct yet coordinated roles to regulate blood glucose homeostasis. Islet dysfunction and specifically failure of the beta cells to secrete adequate insulin are known pr...
Main Authors: | Nathan Lawlor, Michael L. Stitzel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-09-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877819305629 |
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