X-ray structure reveals a new class and provides insight into evolution of alkaline phosphatases.

The alkaline phosphatase (AP) is a bi-metalloenzyme of potential applications in biotechnology and bioremediation, in which phosphate monoesters are nonspecifically hydrolysed under alkaline conditions to yield inorganic phosphate. The hydrolysis occurs through an enzyme intermediate in which the ca...

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Bibliographic Details
Main Authors: Subhash C Bihani, Amit Das, Kayzad S Nilgiriwala, Vishal Prashar, Michel Pirocchi, Shree Kumar Apte, Jean-Luc Ferrer, Madhusoodan V Hosur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3145672?pdf=render

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