Production of a recombinant peroxidase in different glyco-engineered Pichia pastoris strains: a morphological and physiological comparison

Production of a recombinant peroxidase in different glyco-engineered Pichia pastoris strains: a morphological and physiological comparison

Abstract Background The methylotrophic yeast Pichia pastoris is a common host for the production of recombinant proteins. However, hypermannosylation hinders the use of recombinant proteins from yeast in most biopharmaceutical applications. Glyco-engineered yeast strains produce more homogeneously g...

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Bibliographic Details
Main Authors: Alexander Pekarsky, Lukas Veiter, Vignesh Rajamanickam, Christoph Herwig, Clemens Grünwald-Gruber, Friedrich Altmann, Oliver Spadiut
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Microbial Cell Factories
Subjects:
Pichia pastoris
SuperMan5
OCH1
Bioreactor
Cellular agglomeration
Flow cytometry
Online Access:http://link.springer.com/article/10.1186/s12934-018-1032-6

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http://link.springer.com/article/10.1186/s12934-018-1032-6

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