Effects of endogenous inflammation signals elicited by nerve growth factor, interferon-γ, and interleukin-4 on peripheral nerve regeneration

Effects of endogenous inflammation signals elicited by nerve growth factor, interferon-γ, and interleukin-4 on peripheral nerve regeneration

Abstract Background Large gap healing is a difficult issue in the recovery of peripheral nerve injury. The present study provides in vivo trials of silicone rubber chambers filled with collagen containing IFN-γ or IL-4 to bridge a 15 mm sciatic nerve defect in rats. Fillings of NGF and normal saline...

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Bibliographic Details
Main Authors: Chien-Fu Liao, Chung-Chia Chen, Yu-Wen Lu, Chun-Hsu Yao, Jia-Horng Lin, Tzong-Der Way, Tse-Yen Yang, Yueh-Sheng Chen
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Biological Engineering
Subjects:
Inflammation signals
NGF
IFN-γ
IL-4
Peripheral nerve regeneration
Online Access:http://link.springer.com/article/10.1186/s13036-019-0216-x

Internet

http://link.springer.com/article/10.1186/s13036-019-0216-x

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