An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen

Current work proposes an inimitable composite, with great electrical conductivity and quite enhanced surface area, (including conducting polymers (poly (cathechol)), Cu2O–carbon dots and green synthesized gold nanoparticles) for detecting acute carcinoembryonic antigen.<br /> At current work,...

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Main Authors: Mohammad Mazloum-Ardakani, Behnaz Barazesh, Seyed Mohammad Moshtaghioun
Format: Article
Language:English
Published: Nanoscience and Nanotechnology Research Center, University of Kashan 2019-10-01
Series:Journal of Nanostructures
Subjects:
Online Access:http://jns.kashanu.ac.ir/article_80539_d7c7045eea15c1f5047a4534685bc793.pdf
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spelling doaj-715b50fc7bcb43ba96af47a06e1761a02020-11-25T00:34:56ZengNanoscience and Nanotechnology Research Center, University of KashanJournal of Nanostructures2251-78712251-788X2019-10-019465966810.22052/JNS.2019.04.00880539An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigenMohammad Mazloum-Ardakani0Behnaz Barazesh1Seyed Mohammad Moshtaghioun2Department of Chemistry, Faculty of Science, Yazd University, Yazd, IranDepartment of Chemistry, Faculty of Science, Yazd University, Yazd, IranMoshtaghiounCurrent work proposes an inimitable composite, with great electrical conductivity and quite enhanced surface area, (including conducting polymers (poly (cathechol)), Cu2O–carbon dots and green synthesized gold nanoparticles) for detecting acute carcinoembryonic antigen.<br /> At current work, the electropolymerization was offered instead of enzyme-catalyzed polymerization of poly (catechol). <br /> Four cost-effective electrochemical techniques (Differential Pulse Voltammetry, Electrochemical Impedance Spectroscopy, Cyclic Voltammetry and Crono amperometry) were engaged to investigate aptasensors construction, immobilization, hybridization, sensitivity, selectivity, repeatability, long-term stability and real PCR sample detections.<br /> According to the data, the values of Ipeak is linearly related to the logarithm of the concentrations of carcinoembryonic antigen in the range from 1.0 pg mL-1 to 0.001 g mL-1, with a detection limit of 0.19 pg mL-1 for the target antigen (carcinoembryonic antigen).<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigen.<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigenhttp://jns.kashanu.ac.ir/article_80539_d7c7045eea15c1f5047a4534685bc793.pdfkeywords: conducting polymercarbon quantum dotsgreen synthesizeelctrosynthesizescreen-printed electrodecarcinoembryonic antigen
collection DOAJ
language English
format Article
sources DOAJ
author Mohammad Mazloum-Ardakani
Behnaz Barazesh
Seyed Mohammad Moshtaghioun
spellingShingle Mohammad Mazloum-Ardakani
Behnaz Barazesh
Seyed Mohammad Moshtaghioun
An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
Journal of Nanostructures
keywords: conducting polymer
carbon quantum dots
green synthesize
elctrosynthesize
screen-printed electrode
carcinoembryonic antigen
author_facet Mohammad Mazloum-Ardakani
Behnaz Barazesh
Seyed Mohammad Moshtaghioun
author_sort Mohammad Mazloum-Ardakani
title An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
title_short An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
title_full An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
title_fullStr An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
title_full_unstemmed An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
title_sort aptasensor based on electrosynthesized conducting polymers, cu2o–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
publisher Nanoscience and Nanotechnology Research Center, University of Kashan
series Journal of Nanostructures
issn 2251-7871
2251-788X
publishDate 2019-10-01
description Current work proposes an inimitable composite, with great electrical conductivity and quite enhanced surface area, (including conducting polymers (poly (cathechol)), Cu2O–carbon dots and green synthesized gold nanoparticles) for detecting acute carcinoembryonic antigen.<br /> At current work, the electropolymerization was offered instead of enzyme-catalyzed polymerization of poly (catechol). <br /> Four cost-effective electrochemical techniques (Differential Pulse Voltammetry, Electrochemical Impedance Spectroscopy, Cyclic Voltammetry and Crono amperometry) were engaged to investigate aptasensors construction, immobilization, hybridization, sensitivity, selectivity, repeatability, long-term stability and real PCR sample detections.<br /> According to the data, the values of Ipeak is linearly related to the logarithm of the concentrations of carcinoembryonic antigen in the range from 1.0 pg mL-1 to 0.001 g mL-1, with a detection limit of 0.19 pg mL-1 for the target antigen (carcinoembryonic antigen).<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigen.<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigen
topic keywords: conducting polymer
carbon quantum dots
green synthesize
elctrosynthesize
screen-printed electrode
carcinoembryonic antigen
url http://jns.kashanu.ac.ir/article_80539_d7c7045eea15c1f5047a4534685bc793.pdf
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