An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen
Current work proposes an inimitable composite, with great electrical conductivity and quite enhanced surface area, (including conducting polymers (poly (cathechol)), Cu2O–carbon dots and green synthesized gold nanoparticles) for detecting acute carcinoembryonic antigen.<br /> At current work,...
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Nanoscience and Nanotechnology Research Center, University of Kashan
2019-10-01
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doaj-715b50fc7bcb43ba96af47a06e1761a02020-11-25T00:34:56ZengNanoscience and Nanotechnology Research Center, University of KashanJournal of Nanostructures2251-78712251-788X2019-10-019465966810.22052/JNS.2019.04.00880539An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigenMohammad Mazloum-Ardakani0Behnaz Barazesh1Seyed Mohammad Moshtaghioun2Department of Chemistry, Faculty of Science, Yazd University, Yazd, IranDepartment of Chemistry, Faculty of Science, Yazd University, Yazd, IranMoshtaghiounCurrent work proposes an inimitable composite, with great electrical conductivity and quite enhanced surface area, (including conducting polymers (poly (cathechol)), Cu2O–carbon dots and green synthesized gold nanoparticles) for detecting acute carcinoembryonic antigen.<br /> At current work, the electropolymerization was offered instead of enzyme-catalyzed polymerization of poly (catechol). <br /> Four cost-effective electrochemical techniques (Differential Pulse Voltammetry, Electrochemical Impedance Spectroscopy, Cyclic Voltammetry and Crono amperometry) were engaged to investigate aptasensors construction, immobilization, hybridization, sensitivity, selectivity, repeatability, long-term stability and real PCR sample detections.<br /> According to the data, the values of Ipeak is linearly related to the logarithm of the concentrations of carcinoembryonic antigen in the range from 1.0 pg mL-1 to 0.001 g mL-1, with a detection limit of 0.19 pg mL-1 for the target antigen (carcinoembryonic antigen).<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigen.<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigenhttp://jns.kashanu.ac.ir/article_80539_d7c7045eea15c1f5047a4534685bc793.pdfkeywords: conducting polymercarbon quantum dotsgreen synthesizeelctrosynthesizescreen-printed electrodecarcinoembryonic antigen |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohammad Mazloum-Ardakani Behnaz Barazesh Seyed Mohammad Moshtaghioun |
spellingShingle |
Mohammad Mazloum-Ardakani Behnaz Barazesh Seyed Mohammad Moshtaghioun An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen Journal of Nanostructures keywords: conducting polymer carbon quantum dots green synthesize elctrosynthesize screen-printed electrode carcinoembryonic antigen |
author_facet |
Mohammad Mazloum-Ardakani Behnaz Barazesh Seyed Mohammad Moshtaghioun |
author_sort |
Mohammad Mazloum-Ardakani |
title |
An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen |
title_short |
An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen |
title_full |
An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen |
title_fullStr |
An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen |
title_full_unstemmed |
An aptasensor based on electrosynthesized conducting polymers, Cu2O–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen |
title_sort |
aptasensor based on electrosynthesized conducting polymers, cu2o–carbon dots and biosynthesized gold nanoparticles, for monitoring carcinoembryonic antigen |
publisher |
Nanoscience and Nanotechnology Research Center, University of Kashan |
series |
Journal of Nanostructures |
issn |
2251-7871 2251-788X |
publishDate |
2019-10-01 |
description |
Current work proposes an inimitable composite, with great electrical conductivity and quite enhanced surface area, (including conducting polymers (poly (cathechol)), Cu2O–carbon dots and green synthesized gold nanoparticles) for detecting acute carcinoembryonic antigen.<br /> At current work, the electropolymerization was offered instead of enzyme-catalyzed polymerization of poly (catechol). <br /> Four cost-effective electrochemical techniques (Differential Pulse Voltammetry, Electrochemical Impedance Spectroscopy, Cyclic Voltammetry and Crono amperometry) were engaged to investigate aptasensors construction, immobilization, hybridization, sensitivity, selectivity, repeatability, long-term stability and real PCR sample detections.<br /> According to the data, the values of Ipeak is linearly related to the logarithm of the concentrations of carcinoembryonic antigen in the range from 1.0 pg mL-1 to 0.001 g mL-1, with a detection limit of 0.19 pg mL-1 for the target antigen (carcinoembryonic antigen).<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigen.<br /> Keywords: conducting polymer, carbon quantum dots, green synthesize, elctrosynthesize, screen-printed electrode, carcinoembryonic antigen |
topic |
keywords: conducting polymer carbon quantum dots green synthesize elctrosynthesize screen-printed electrode carcinoembryonic antigen |
url |
http://jns.kashanu.ac.ir/article_80539_d7c7045eea15c1f5047a4534685bc793.pdf |
work_keys_str_mv |
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