Identification and mechanistic analysis of an inhibitor of the CorC Mg2+ transporter

Identification and mechanistic analysis of an inhibitor of the CorC Mg2+ transporter

Summary: The CorC/CNNM family of Na+-dependent Mg2+ transporters is ubiquitously conserved from bacteria to humans. CorC, the bacterial CorC/CNNM family of proteins, is involved in resistance to antibiotic exposure and in the survival of pathogenic microorganisms in their host environment. The CorC/...

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Bibliographic Details
Main Authors: Yichen Huang, Kaijie Mu, Xinyu Teng, Yimeng Zhao, Yosuke Funato, Hiroaki Miki, Weiliang Zhu, Zhijian Xu, Motoyuki Hattori
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Chemical Compound
Membranes
Structural Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003382

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