FKBP5 Exacerbates Impairments in Cerebral Ischemic Stroke by Inducing Autophagy via the AKT/FOXO3 Pathway

FKBP5 Exacerbates Impairments in Cerebral Ischemic Stroke by Inducing Autophagy via the AKT/FOXO3 Pathway

Cerebral ischemic stroke is regarded as one of the most serious diseases in the human central nervous system. The secondary ischemia and reperfusion (I/R) injury increased the difficulty of treatment. Moreover, the latent molecular regulating mechanism in I/R injury is still unclear. Based on our pr...

Full description

Bibliographic Details
Main Authors: Shijia Yu, Mingjun Yu, Zhongqi Bu, Pingping He, Juan Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cerebral ischemic stroke
FKBP5
FOXO3
autophagy
ischemia and reperfusion injury
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00193/full

Similar Items

Similar Items