OLIG2 regulates lncRNAs and its own expression during oligodendrocyte lineage formation

OLIG2 regulates lncRNAs and its own expression during oligodendrocyte lineage formation

Abstract Background Oligodendrocytes, responsible for axon ensheathment, are critical for central nervous system (CNS) development, function, and diseases. OLIG2 is an important transcription factor (TF) that acts during oligodendrocyte development and performs distinct functions at different stages...

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Bibliographic Details
Main Authors: Haichao Wei, Xiaomin Dong, Yanan You, Bo Hai, Raquel Cuevas-Diaz Duran, Xizi Wu, Natasha Kharas, Jia Qian Wu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Biology
Subjects:
Oligodendrocyte development
OLIG2
LncRNAs
Histone modification
Transcriptional regulation
Regulation after transcription
Online Access:https://doi.org/10.1186/s12915-021-01057-6

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