scClassify: sample size estimation and multiscale classification of cells using single and multiple reference

Abstract Automated cell type identification is a key computational challenge in single‐cell RNA‐sequencing (scRNA‐seq) data. To capitalise on the large collection of well‐annotated scRNA‐seq datasets, we developed scClassify, a multiscale classification framework based on ensemble learning and cell...

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Bibliographic Details
Main Authors: Yingxin Lin, Yue Cao, Hani Jieun Kim, Agus Salim, Terence P Speed, David M Lin, Pengyi Yang, Jean Yee Hwa Yang
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20199389