Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice.

Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice.

Interleukin (IL)-17 is emerging as an important cytokine in vaccine-induced protection against tuberculosis disease in animal models. Here we show that compared to parenteral delivery, BCG delivered mucosally enhances cytokine production, including interferon gamma and IL-17, in the lungs. Furthermo...

Full description

Bibliographic Details
Main Authors: Kristin L Griffiths, Elena Stylianou, Hazel C Poyntz, Gareth J Betts, Helen A Fletcher, Helen McShane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3806838?pdf=render

Similar Items

Similar Items