Effect of Bisphosphonates on Orthodontic Tooth Movement—An Update
Bisphosphonates are a synthetic class of pyrophosphate analogues that are powerful inhibitors of bone resorption which are commonly used as a medication for the prevention and therapy of osteoporosis and osteopenia, also used to treat tumor diseases. As it affects bone metabolism, it is said to ha...
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doaj-712d2cbfdbd94fa5a6755edb88a40ca02020-11-25T03:39:28ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-04-0194ZE01ZE0510.7860/JCDR/2015/11162.5769Effect of Bisphosphonates on Orthodontic Tooth Movement—An UpdateSindhuja Krishnan0Saravana Pandian1Aravind Kumar. S2Post Graduation, Department of Orthodontics and Dentofacial Orthopaedics, Saveetha Dental College, Saveetha, University, Chennai, Tamilnadu, India.Post Graduation, Department of Orthodontics and Dentofacial Orthopaedics, Saveetha Dental College, Saveetha, University, Chennai, Tamilnadu, India. Professor, Department of Orthodontics and Dentofacial Orthopaedics, Saveetha Dental College, Saveetha, University, Chennai, Tamilnadu, India. Bisphosphonates are a synthetic class of pyrophosphate analogues that are powerful inhibitors of bone resorption which are commonly used as a medication for the prevention and therapy of osteoporosis and osteopenia, also used to treat tumor diseases. As it affects bone metabolism, it is said to have an influence on orthodontic treatment and tooth movement. Also, this review gives an insight into the reported effects of Bisphosphonate medication in literature highlighting the status quo of scientific research regarding effects of Bisphosphonates on orthodontic tooth movement. A systematic literature search was done in Medline database (Pubmed) for the appropriate keywords. Manual handsearch was also done. From the available evidence it can be concluded that the duration of orthodontic treatment is increased for patients under Bisphosphonate therapy as they interfere with the osteoclastic resorption. However, they may be beneficial for anchorage procedures. Further long term prospective randomized controlled trials are required to assess possible benefits and adverse effects of bisphosphonate treatment, before Bisphosphonates can be therapeutically used in orthodontics.https://jcdr.net/articles/PDF/5769/11162_CE(Ra1)_F(GH)_PF1(NJAK)_PFA(AK)_PFA2(AK)_PF2(PAG).pdfbisphosphonatesorthodontic tooth movementorthodontic anchorageroot resorption |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sindhuja Krishnan Saravana Pandian Aravind Kumar. S |
spellingShingle |
Sindhuja Krishnan Saravana Pandian Aravind Kumar. S Effect of Bisphosphonates on Orthodontic Tooth Movement—An Update Journal of Clinical and Diagnostic Research bisphosphonates orthodontic tooth movement orthodontic anchorage root resorption |
author_facet |
Sindhuja Krishnan Saravana Pandian Aravind Kumar. S |
author_sort |
Sindhuja Krishnan |
title |
Effect of Bisphosphonates on Orthodontic Tooth Movement—An Update |
title_short |
Effect of Bisphosphonates on Orthodontic Tooth Movement—An Update |
title_full |
Effect of Bisphosphonates on Orthodontic Tooth Movement—An Update |
title_fullStr |
Effect of Bisphosphonates on Orthodontic Tooth Movement—An Update |
title_full_unstemmed |
Effect of Bisphosphonates on Orthodontic Tooth Movement—An Update |
title_sort |
effect of bisphosphonates on orthodontic tooth movement—an update |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2015-04-01 |
description |
Bisphosphonates are a synthetic class of pyrophosphate analogues that are powerful inhibitors of bone resorption which are commonly
used as a medication for the prevention and therapy of osteoporosis and osteopenia, also used to treat tumor diseases. As it affects
bone metabolism, it is said to have an influence on orthodontic treatment and tooth movement. Also, this review gives an insight
into the reported effects of Bisphosphonate medication in literature highlighting the status quo of scientific research regarding effects
of Bisphosphonates on orthodontic tooth movement. A systematic literature search was done in Medline database (Pubmed) for the
appropriate keywords. Manual handsearch was also done. From the available evidence it can be concluded that the duration of
orthodontic treatment is increased for patients under Bisphosphonate therapy as they interfere with the osteoclastic resorption.
However, they may be beneficial for anchorage procedures. Further long term prospective randomized controlled trials are required
to assess possible benefits and adverse effects of bisphosphonate treatment, before Bisphosphonates can be therapeutically used
in orthodontics. |
topic |
bisphosphonates orthodontic tooth movement orthodontic anchorage root resorption |
url |
https://jcdr.net/articles/PDF/5769/11162_CE(Ra1)_F(GH)_PF1(NJAK)_PFA(AK)_PFA2(AK)_PF2(PAG).pdf |
work_keys_str_mv |
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