Poor Sensitivity of Fecal Gluten Immunogenic Peptides and Serum Antibodies to Detect Duodenal Mucosal Damage in Celiac Disease Monitoring

Poor Sensitivity of Fecal Gluten Immunogenic Peptides and Serum Antibodies to Detect Duodenal Mucosal Damage in Celiac Disease Monitoring

A lifelong gluten-free diet (GFD) is the only current treatment for celiac disease (CD), but strict compliance is complicated. Duodenal biopsies are the “gold standard” method for diagnosing CD, but they are not generally recommended for disease monitoring. We evaluated the sensitivity and specifici...

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Bibliographic Details
Main Authors: Emilio J. Laserna-Mendieta, María José Casanova, Ángel Arias, Laura Arias-González, Pedro Majano, Luis Alberto Mate, Carlos Humberto Gordillo-Vélez, Mirella Jiménez, Teresa Angueira, Emilia Tébar-Romero, María Jesús Carrillo-Ramos, María Ángeles Tejero-Bustos, Javier P. Gisbert, Cecilio Santander, Alfredo J. Lucendo
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Nutrients
Subjects:
celiac disease
gluten-free diet monitoring
Marsh–Oberhüber type
gluten immunogenic peptides
anti-tissue transglutaminase antibodies
diagnostic accuracy
Online Access:https://www.mdpi.com/2072-6643/13/1/98

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