Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks

Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks

Abstract Background Human induced pluripotent stem (iPS) cells have revolutionised research and spark hopes for future tissue replacement therapies. To obtain high cell numbers, iPS cells can be expanded indefinitely. However, as long-term expansion can compromise cell integrity and quality, we set...

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Bibliographic Details
Main Authors: David Brenière-Letuffe, Aya Domke-Shibamiya, Arne Hansen, Thomas Eschenhagen, Boris Fehse, Kristoffer Riecken, Justus Stenzig
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Stem Cell Research & Therapy
Subjects:
Induced pluripotent stem cells
Stem cell culture
RGB marking
Clonal diversity
Induced pluripotent stem cell quality
Online Access:http://link.springer.com/article/10.1186/s13287-018-0893-2

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