Effects of KB-R9032, a new Na+/H+ Exchange Inhibitor, on Canine Coronary Occlusion/Reperfusion-Induced Ventricular Arrhythmias

We investigated the effects of KB-R9032 (N-(4-isopropyl-2,2-dimethyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl) guanidine methanesulfonate), a new Na+/H+ exchange inhibitor, on a coronary artery occlusion/reperfusion-induced arrhythmia model in pentobarbital anesthetized dogs. KB-R9032 reduc...

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Bibliographic Details
Main Authors: Chikaomi Yamada, YiXue Xue, Daisuke Chino, Keitaro Hashimoto
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319321565