A Bifunctional Molecule with Lectin and Protease Inhibitor Activities Isolated from <i>Crataeva tapia</i> Bark Significantly Affects Cocultures of Mesenchymal Stem Cells and Glioblastoma Cells

A Bifunctional Molecule with Lectin and Protease Inhibitor Activities Isolated from <i>Crataeva tapia</i> Bark Significantly Affects Cocultures of Mesenchymal Stem Cells and Glioblastoma Cells

Currently available drugs for treatment of glioblastoma, the most aggressive brain tumor, remain inefficient, thus a plethora of natural compounds have already been shown to have antimalignant effects. However, these have not been tested for their impact on tumor cells in their microenvironment-simu...

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Bibliographic Details
Main Authors: Camila Ramalho Bonturi, Mariana Cristina Cabral Silva, Helena Motaln, Bruno Ramos Salu, Rodrigo da Silva Ferreira, Fabricio Pereira Batista, Maria Tereza dos Santos Correia, Patrícia Maria Guedes Paiva, Tamara Lah Turnšek, Maria Luiza Vilela Oliva
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
CrataBL
glioblastoma
mesenchymal stem cells
microenvironment
plant lectin
protease inhibitor
Online Access:https://www.mdpi.com/1420-3049/24/11/2109

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