Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany

Abstract Background This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower HRQoL independent of metabolic health status and potential confounders,...

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Main Authors: Julia Truthmann, Gert B. M. Mensink, Anja Bosy-Westphal, Ulfert Hapke, Christa Scheidt-Nave, Anja Schienkiewitz
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Health and Quality of Life Outcomes
Subjects:
Sex
Online Access:http://link.springer.com/article/10.1186/s12955-017-0688-7
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spelling doaj-710b63d488114bfea9bb78c2068b45bb2020-11-24T21:56:32ZengBMCHealth and Quality of Life Outcomes1477-75252017-06-011511710.1186/s12955-017-0688-7Physical health-related quality of life in relation to metabolic health and obesity among men and women in GermanyJulia Truthmann0Gert B. M. Mensink1Anja Bosy-Westphal2Ulfert Hapke3Christa Scheidt-Nave4Anja Schienkiewitz5Department of Epidemiology and Health Monitoring, Robert Koch InstituteDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteInstitute of Nutritional Medicine, University of HohenheimDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteDepartment of Epidemiology and Health Monitoring, Robert Koch InstituteAbstract Background This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower HRQoL independent of metabolic health status and potential confounders, and (2) whether associations are similar in men and women. Methods We used cross-sectional data from the German Health Interview and Examination Survey 2008–11. Physical HRQoL was measured using the Short Form-36 version 2 physical component summary (PCS) score. Based on harmonized ATPIII criteria for the definition of the metabolic health and a body mass index ≥ 30 kg/m2 to define obesity, individuals were classified as metabolically healthy non-obese (MHNO), metabolically unhealthy non-obese (MUNO), metabolically healthy obese (MHO), and metabolically unhealthy obese (MUO). Sex-specific analyses including multivariable linear regression analyses were based on PCS as the dependent variable, metabolic health and obesity category as the independent variable with three categories and MHNO as the reference, and age, education, lifestyle and comorbidities as confounders. Results This study included 6860 participants (3298 men, 3562 women). Compared to MHNO, all other metabolic health and obesity categories had significantly lower PCS in both sexes. As reflected by the beta coefficients [95% confidence interval] from bivariable linear regression models, a significant inverse association with PCS was strongest for MUO (men: −7.0 [−8.2; −5.8]; women: −9.0 [−10.2; −7.9]), intermediate for MUNO (men: −4.2 [−5.3; −3.1]; women: −5.6 [−6.8; −4.4]) and least pronounced for MHO (men: −2.2 [−3.6; −0.8]; women −3.9 [−5.4; −2.5]). Differences in relation to MHNO remained statistically significant for all groups after adjusting for confounders, but decreased in particular for MUNO (men:–1.3 [−2.3; −0.3]; women: −1.5 [−2.7; −0.3]. Conclusions Obesity was significantly related to lower physical HRQoL, independent of metabolic health status. Potential confounders including age, educational status, health-related behaviors, and comorbidities explained parts of the inverse relationship. Associations were evident in both sexes and consistently more pronounced among women than men.http://link.springer.com/article/10.1186/s12955-017-0688-7Metabolically healthy obesitySF-36Physical component summarySexSocio-economic statusLifestyle
collection DOAJ
language English
format Article
sources DOAJ
author Julia Truthmann
Gert B. M. Mensink
Anja Bosy-Westphal
Ulfert Hapke
Christa Scheidt-Nave
Anja Schienkiewitz
spellingShingle Julia Truthmann
Gert B. M. Mensink
Anja Bosy-Westphal
Ulfert Hapke
Christa Scheidt-Nave
Anja Schienkiewitz
Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany
Health and Quality of Life Outcomes
Metabolically healthy obesity
SF-36
Physical component summary
Sex
Socio-economic status
Lifestyle
author_facet Julia Truthmann
Gert B. M. Mensink
Anja Bosy-Westphal
Ulfert Hapke
Christa Scheidt-Nave
Anja Schienkiewitz
author_sort Julia Truthmann
title Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany
title_short Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany
title_full Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany
title_fullStr Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany
title_full_unstemmed Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany
title_sort physical health-related quality of life in relation to metabolic health and obesity among men and women in germany
publisher BMC
series Health and Quality of Life Outcomes
issn 1477-7525
publishDate 2017-06-01
description Abstract Background This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower HRQoL independent of metabolic health status and potential confounders, and (2) whether associations are similar in men and women. Methods We used cross-sectional data from the German Health Interview and Examination Survey 2008–11. Physical HRQoL was measured using the Short Form-36 version 2 physical component summary (PCS) score. Based on harmonized ATPIII criteria for the definition of the metabolic health and a body mass index ≥ 30 kg/m2 to define obesity, individuals were classified as metabolically healthy non-obese (MHNO), metabolically unhealthy non-obese (MUNO), metabolically healthy obese (MHO), and metabolically unhealthy obese (MUO). Sex-specific analyses including multivariable linear regression analyses were based on PCS as the dependent variable, metabolic health and obesity category as the independent variable with three categories and MHNO as the reference, and age, education, lifestyle and comorbidities as confounders. Results This study included 6860 participants (3298 men, 3562 women). Compared to MHNO, all other metabolic health and obesity categories had significantly lower PCS in both sexes. As reflected by the beta coefficients [95% confidence interval] from bivariable linear regression models, a significant inverse association with PCS was strongest for MUO (men: −7.0 [−8.2; −5.8]; women: −9.0 [−10.2; −7.9]), intermediate for MUNO (men: −4.2 [−5.3; −3.1]; women: −5.6 [−6.8; −4.4]) and least pronounced for MHO (men: −2.2 [−3.6; −0.8]; women −3.9 [−5.4; −2.5]). Differences in relation to MHNO remained statistically significant for all groups after adjusting for confounders, but decreased in particular for MUNO (men:–1.3 [−2.3; −0.3]; women: −1.5 [−2.7; −0.3]. Conclusions Obesity was significantly related to lower physical HRQoL, independent of metabolic health status. Potential confounders including age, educational status, health-related behaviors, and comorbidities explained parts of the inverse relationship. Associations were evident in both sexes and consistently more pronounced among women than men.
topic Metabolically healthy obesity
SF-36
Physical component summary
Sex
Socio-economic status
Lifestyle
url http://link.springer.com/article/10.1186/s12955-017-0688-7
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