Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition.

Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition.

In response to inflammation, mesenchymal stem cells (MSCs) are known to migrate to tissue injury sites to participate in immune modulation, tissue remodeling and wound healing. Tumors apply persistent mechanical and pathological stress to tissues and causes continual infiltration of MSCs. Here, we d...

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Bibliographic Details
Main Authors: Yingying Jing, Zhipeng Han, Yan Liu, Kai Sun, Shanshan Zhang, Guocheng Jiang, Rong Li, Lu Gao, Xue Zhao, Dong Wu, Xiong Cai, Mengchao Wu, Lixin Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429457?pdf=render

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