CCR2+ migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice.

CCR2+ migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice.

Complex interactions between HSV-1 and infiltrating immune cells play important roles in establishing localized, acute virus replication as well as chronic latent infection. The extent and duration of initial virus replication are the key determinants of subsequent pathologic inflammatory responses...

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Bibliographic Details
Main Authors: Dhong Hyun Lee, Ujjaldeep Jaggi, Homayon Ghiasi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215727

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