DLS: A Link Prediction Method Based on Network Local Structure for Predicting Drug-Protein Interactions

DLS: A Link Prediction Method Based on Network Local Structure for Predicting Drug-Protein Interactions

The studies on drug-protein interactions (DPIs) had significant for drug repositioning, drug discovery, and clinical medicine. The biochemical experimentation (in vitro) requires a long time and high cost to be confirmed because it is difficult to estimate. Therefore, a feasible solution is to predi...

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Bibliographic Details
Main Authors: Wei Wang, Hehe Lv, Yuan Zhao, Dong Liu, Yongqing Wang, Yu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
drug-protein interactions
network analysis
link prediction
DPI local structural similarity
network local structure
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00330/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00330/full

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