A sterospecific synthesis of 7α-hydroxycholesterol

The five step synthesis of 7α-hydroxycholesterol utilizes the solvolysis of 7α-bromocholesterol benzoate with potassium acetate in acetic acid as the key step in controlling the stereospecificity of the reaction sequence. This reaction yields 7α-acetoxycholesterol benzoate with retention of configur...

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Bibliographic Details
Main Authors: D B Johnson, L Lack
Format: Article
Language:English
Published: Elsevier 1976-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752037022X