The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation

The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation

Advancements in the early detection of cancer coupled with improved surgery, radiotherapy, and adjuvant therapy led to substantial increase in patient survival. Nevertheless, cancer metastasis is the leading cause of death in several cancer patients. The majority of these deaths are associated with...

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Bibliographic Details
Main Authors: Amit S. Yadav, Poonam R. Pandey, Ramesh Butti, N. N. V. Radharani, Shamayita Roy, Shaileshkumar R. Bhalara, Mahadeo Gorain, Gopal C. Kundu, Dhiraj Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Oncology
Subjects:
cancer metastasis
dormancy
reactivation
tumor microenvironment
epithelial to mesenchymal transition
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00072/full

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