Comparative in vivo antiangiogenic effects of calreticulin from Trypanosoma cruzi and Homo sapiens sapiens

Angiogenesis is a complex multi-step process of neovascularization arising from preexisting blood vessels whose generation is regulated by pro- and anti-angiogenic factors. Both Trypanosoma cruzi calreticulin (TcCRT) and its human counterpart (HuCRT) are antiangiogenic. This is the first report wher...

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Bibliographic Details
Main Authors: Victor Toledo, Galia Ramírez, Carolina Valck, Nandy López, Carolina H Ribeiro, Ismael Maldonado, Lorena Aguilar, David Lemus, Arturo Ferreira
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000300004