A helminth immunomodulator exploits host signaling events to regulate cytokine production in macrophages.

Parasitic worms alter their host's immune system to diminish the inflammatory responses directed against them, using very efficient immunomodulating molecules. We have previously shown that the helminth immunomodulator cystatin (AvCystatin) profoundly reduces the progression of inflammatory dis...

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Bibliographic Details
Main Authors: Christian Klotz, Thomas Ziegler, Ana Sofia Figueiredo, Sebastian Rausch, Matthew R Hepworth, Nadja Obsivac, Christine Sers, Roland Lang, Peter Hammerstein, Richard Lucius, Susanne Hartmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21253577/pdf/?tool=EBI