Epidemiology and pathobiology of SARS-CoV-2 (COVID-19) in comparison with SARS, MERS: An updated overview of current knowledge and future perspectives

• Main Authors: Balasubramanian Ganesh, Thangarasu Rajakumar, Mathiyazhakan Malathi, Natesan Manikandan, Jaganathasamy Nagaraj, Aridoss Santhakumar, Arumugam Elangovan, Yashpal Singh Malik
• Format: Article
• Language: English
• Published: Elsevier 2021-04-01
• Series: Clinical Epidemiology and Global Health
• Subjects: COVID-19; SARS-CoV-2; SARS-CoV; MERS-CoV; Epidemiology; Pathobiology
• Online Access: http://www.sciencedirect.com/science/article/pii/S2213398420302645
• ISSN: 2213-3984

Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is the causative etiology of ‘Corona Virus Disease-2019’ (COVID-19); formerly referred as ‘novel-Coronavirus-2019’. It was originated in Wuhan city, Hubei province, China in early December 2019. The World Health Organization (WHO) declared it as ‘Public Health Emergency of International Concern’ due to their rapid transmission and causing public and health-care-related casualties worldwide. This review provides an updated overview of COVID-19 (SARS-CoV-2), in comparison with the etiologies of the same group viz. SARS and MERS and also its future perspectives for planning appropriate strategies for prevention, control and treatment modalities to avert similar catastrophe in near future.