Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function

Background The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. Tests for positive selection can identify appare...

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Bibliographic Details
Main Authors: Alejandro Berrio, Valerie Gartner, Gregory A. Wray
Format: Article
Language:English
Published: PeerJ Inc. 2020-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10234.pdf

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