Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome

Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome

<p>Abstract</p> <p>Background</p> <p>Normal post-squalene cholesterol biosynthesis is important for mammalian embryonic development. Neonatal mice lacking functional dehydrocholesterol Δ7-reductase (Dhcr7), a model for the human disease of Smith-Lemli-Opitz syndrome, di...

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Bibliographic Details
Main Authors: Tint G Stephen, Oatis John, Phelps Aimee L, Chen Jianliang, Wessels Andy, Yu Hongwei, Patel Shailendra B
Format: Article
Language:English
Published: BMC 2004-02-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/4/1

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