mRNA decapping is an evolutionarily conserved modulator of neuroendocrine signaling that controls development and ageing

mRNA decapping is an evolutionarily conserved modulator of neuroendocrine signaling that controls development and ageing

Eukaryotic 5’−3’ mRNA decay plays important roles during development and in response to stress, regulating gene expression post-transcriptionally. In Caenorhabditis elegans, deficiency of DCAP-1/DCP1, the essential co-factor of the major cytoplasmic mRNA decapping enzyme, impacts normal development,...

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Bibliographic Details
Main Authors: Fivos Borbolis, John Rallis, George Kanatouris, Nikolitsa Kokla, Antonis Karamalegkos, Christina Vasileiou, Katerina M Vakaloglou, George Diallinas, Dimitrios J Stravopodis, Christos G Zervas, Popi Syntichaki
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
Caenorhabditis elegans
Drosophila melanogaster
DCAP-1/DCP1
iongevity
ins-7
wing development
Online Access:https://elifesciences.org/articles/53757

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