Identification of mechanosensitive genes during embryonic bone formation.

Although it is known that mechanical forces are needed for normal bone development, the current understanding of how biophysical stimuli are interpreted by and integrated with genetic regulatory mechanisms is limited. Mechanical forces are thought to be mediated in cells by "mechanosensitive&qu...

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Bibliographic Details
Main Authors: Niamh C Nowlan, Patrick J Prendergast, Paula Murphy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2592698?pdf=render