The Role of Nucleases and Nucleic Acid Editing Enzymes in the Regulation of Self-Nucleic Acid Sensing
Detection of microbial nucleic acids by the innate immune system is mediated by numerous intracellular nucleic acids sensors. Upon the detection of nucleic acids these sensors induce the production of inflammatory cytokines, and thus play a crucial role in the activation of anti-microbial immunity....
Main Authors: | Pauline Santa, Anne Garreau, Lee Serpas, Amandine Ferriere, Patrick Blanco, Chetna Soni, Vanja Sisirak |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-02-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.629922/full |
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