Pangenome Analysis of Mycobacterium Tuberculosis Reveals Core-Drug Targets and Screening of Promising Lead Compounds for Drug Discovery

Pangenome Analysis of Mycobacterium Tuberculosis Reveals Core-Drug Targets and Screening of Promising Lead Compounds for Drug Discovery

Tuberculosis, caused by <i>Mycobacterium tuberculosis</i> (<i>M. tuberculosis</i>), is one of the leading causes of human deaths globally according to the WHO TB 2019 report. The continuous rise in multi- and extensive-drug resistance in <i>M. tuberculosis</i> bro...

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Bibliographic Details
Main Authors: Hamza Arshad Dar, Tahreem Zaheer, Nimat Ullah, Syeda Marriam Bakhtiar, Tianyu Zhang, Muhammad Yasir, Esam I. Azhar, Amjad Ali
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antibiotics
Subjects:
<i>Mycobacterium tuberculosis</i>
pangenome
drug targets
molecular docking
lead compounds
drug discovery
Online Access:https://www.mdpi.com/2079-6382/9/11/819

Internet

https://www.mdpi.com/2079-6382/9/11/819

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