Successful pregnancy outcome in paroxysmal nocturnal hemoglobinuria (PNH) following escalated eculizumab dosing to control breakthrough hemolysis

Successful pregnancy outcome in paroxysmal nocturnal hemoglobinuria (PNH) following escalated eculizumab dosing to control breakthrough hemolysis

Pregnancy in women with paroxysmal nocturnal hemoglobinuria (PNH) is associated with increased maternal and fetal morbidity and mortality. There is limited published experience regarding therapy of PNH during pregnancy. We describe a case of a 30 year old female with hypoplastic myelodysplastic synd...

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Bibliographic Details
Main Authors: Ruby Sharma, Alla Keyzner, Johnson Liu, Thomas Bradley, Steven L. Allen
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Leukemia Research Reports
Subjects:
Breakthrough PNH hemolysis complicating pregnancy
Escalated eculizumab dosing
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048915000059

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